Histogen’s technology is based on the discovery that growing fibroblast cells under simulated embryonic conditions induces them to become multipotent stem cells. The environment created by Histogen’s proprietary process mimics the conditions within the womb – very low oxygen and suspension. When cultured under these conditions, the induced multipotent stem cells generate biological materials that stimulate a patient’s own stem cells to activate and regenerate tissue.
From Histogen’s single proprietary manufacturing process, two key materials are produced: 1) a soluble multipotent cell conditioned media (CCM) that is the starting material for products for hair growth, skin care and other applications, and 2) an insoluble extracellular matrix (ECM) for applications such as orthopedics, wound care and soft tissue augmentation.
Histogen’s one technology, numerous applications approach offers a continuum of product introduction opportunities, from lead aesthetic applications such as hair regrowth and skincare, to therapeutics including orthopedics and wound healing.