ExceltrixTM
ExceltrixTM, Histogen's human Extracellular Matrix (ECM) contains all of the materials found in young, healthy tissue. When newborn cells are seeded onto the bead-like structure and conditioned in the media, the cells attach, divide and secrete ECM proteins and growth factors, forming a human, structurally functional tissue/ substance.
Histogen's Exceltrix has been shown to support the active proliferation of human cells, as well as the rapid in-growth of cells. Other benefits include:
- Rapid host cell integration and improved healing
- Elimination of immunogenicity
- Consistent product composition and performance, particularly human dermis and fascia lata
- Elimination of concern regarding viral and disease transmission from animal and human tissues, such as BSE from bovine tissues and TSE from human tissues
- Reduction of erosion of host tissues, in comparison to synthetics
- Reasonable product costs and elimination of availability issues due to manufacturing expertise and up-scaling potential
Histogen has identified numerous potential product applications including but not limited to:
- Coatings for medical devices
- Dermal filler for the aesthetics market
- Oncology applications
- Advanced wound care (wound healing patches, etc)
- Dental and periodontal applications
© Histogen Inc., CA 92101